Skip to main content

Wine, cheese, and the French Paradox in Walla Walla


I enjoyed participating in the recent Wine BloggersConference in Walla Walla, where I gave a talk on
wine and health, and I have been looking for a way to tie it all together. Since I write about wine and health, I’m in a niche slot. I don’t review wines, like most bloggers at the conference, and I don’t write about lifestyle per se. But I believe I have found the link, albeit unexpectedly, in the Wine and Cheese Pairing with Cheeses of Europe session! The “Cheese Twins” gave a dynamic and entertaining presentation but usually I think of cheese in the same category as wine and alcohol: Justifiable indulgences but not what most would consider health food. Then I remembered a paper from a few years ago that suggested that cheese, not wine, may actually be the basis of the French Paradox.

How cheese might explain the French Paradox


    Here’s the idea, as proposed by in a 2012 publication[i] in the journal Medical Hypotheses:  The French Paradox is distinctly French, with the link to red wine less prominent in other parts of the world. There was the idea that it was attributable to resveratrol, wine’s miracle molecule, but there isn’t enough resveratrol in wine to fully explain why the French get away with their high fat diet. Cheese, being another prominent component of the French diet, needs to at least be accounted for.     Then research began to come out revealing that cheese, especially of the molded varieties, actually has positive effects on cholesterol metabolism, lipid profile, and “inflammatory status.” Evidence showed that these benefits may be due to certain peptides (protein fragments) that occur in higher amounts in molded cheeses such as Roquefort.  (One of these peptides is called roquefortine.) Yes, it appears that cheese may actually be heart-healthy, despite packing doses of salt and triple cream well beyond the usual recommended limits.
    To be fair, the research on cheese as a potentially heart-healthy dietary constituent is in its infancy, while scientific literature on wine and health is massive. There is a recent prospective multinational study[ii] finding dairy intake linked to better heart health, but the correlation was stronger for milk and yogurt than for cheese. On the other hand, a meta-analysis of 29 different studies found a positive relationship to heart health only for fermented dairy such as cheese and yogurt, not total dairy intake.[iii]
It’s also worth noting that the authors of the Medical Hypothesis paper are from a supplement manufacturer, not an academic research lab. In the end, I think it’s most likely that the French Paradox results from a combination of the way that wine, other dietary constituents, and mealtime habits are ingrained in the traditional French way of living. Wine consumption in France, at least when the Paradox came to light, was regular and consistent, just as cheese is a routine course at the end of a meal. We would expect the effect to be less obvious in other cultures, especially where wine is not made or the climate not suitable for dairy production. Sadly, the paradox is diminishing even in France as drinking habits go global.


     So while the cheese twins might be a notable pair of heartthrobs, on the question of heart health it’s wine and cheese that made a beautiful twosome in Walla Walla.




[i] Petyaev IM, Bashmakov YK. Could cheese be the missing piece in the French paradox puzzle? Med Hypotheses 2012 Dec;79(6):746-9. 2012 Sep 13.

[ii] PURE study investigators.  Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study. Lancet. 2018 Sep 11. pii: S0140-6736(18)31812-9.

[iii] Guo J, Astrup A, Lovegrove JA, Gijsbers L, Givens DI, Soedamah-Muthu SS. Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies.
Eur J Epidemiol. 2017 Apr;32(4):269-287.




Comments

Popular posts from this blog

Revisiting resveratrol: new findings rekindle anti-aging debate

Just when we thought the bloom was off the rosé for resveratrol, the anti-oxidant polyphenol from red wine with multiple anti-aging properties, along comes new research giving life to the debate. But first a bit of background: As I detailed in my book Age Gets Better with Wine , it is well-documented that wine drinkers live longer and have lower rates of many diseases of aging. Much or the credit for this has been given to resveratrol, though there isn’t nearly enough of it in wine to explain the effects. Nevertheless, I dubbed it the “miracle molecule” and when it was reported to activate a unique life-extension phenomenon via a genetic trigger called SIRT, an industry was born, led by Sirtris Pharmaceuticals, quickly acquired by pharma giant Glaxo. The hope was that resveratrol science could lead to compounds enabling people to live up to 150 years and with a good quality of life. But alas, researchers from other labs could not duplicate the results, and clinical studies disa

Which came first: Beer or wine? (or something else?)

Actually neither beer nor wine was the first fermented beverage, and wine arguably has a closer connection to health, but recent evidence indicates that humans developed the ability to metabolize alcohol long before we were even human. The uniquely human ability to handle alcohol comes from the digestive enzyme alcohol dehydrogenase, or ADH4. A new science called paleogenetics identifies the emergence of the modern version of the ADH4 gene in our ape ancestors some 10 million years ago. Interestingly, this corresponds to the time when our arboreal forebears transitioned to a nomadic lifestyle on the ground. We went from swinging from tree limbs to walking upright, and the rest is history. Understanding the circumstances that led to perpetuation of the ADH4 mutation may contain clues to what made us human in the first place. How the ability to metabolize alcohol made us human Paleogenetecist Matthew Carrigan has an idea about how this happened . Arboreal species rely on fruit tha