wine and health

Not long after enrolling the first patients in the much hyped prospective study on alcohol and health, the National Institutes of Health recently announced that they were pulling the plug. I am actually more surprised that they ever got it off the ground in the first place. As I wrote a year ago when the study was still in its planning stages, there were too many competing interests, criticisms of the study design, and concerns about funding to expect that whatever results came out would be universally accepted. Nevertheless, I am disappointed. The study, called Moderate Alcohol and Cardiovascular Health Trial (MACH) was intended to provide hard evidence about the health effects of moderate alcohol consumption by prospectively assigning subjects with heart disease to one drink per day or not drinking, which they were to follow for up to 10 years. Most existing data on the question is retrospective, or simply tracks a subject population according to their drinking preferences, w...

What used to be accepted as gospel – that moderate drinkers are healthier than nondrinkers or heavy drinkers – has been challenged in recent years, and a new study to be conducted by the National Institutes of Health aims to settle the question once and for all. The study plans to enroll about 8,000 volunteers aged 50 or older from around the world, who will be assigned to avoid drinking or have one drink per day for 6 years. The lack of such large scale prospective studies is one reason why the question of alcohol’s influence on health and longevity remains subject to debate. However I am not sure the study will yield the answers it seeks to, but not for the reasons others are already finding to criticize the project.  It’s an ambitious undertaking, with an equally ambitious price tag of US$100 million. The plan is for most of the money to come from the alcoholic beverage industry through grants, and $68 million has reportedly already been pledged. Skeptics point out that many...