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Showing posts with the label biogenic amines

Hangover-free wine from engineered yeast? Good wine is already hangover-free.

The promise of hangover-free wine has been in the news this week, based on new gene splicing techniques to manipulate the yeast used in fermentation. Using an enzyme called a “genome knife” researchers have been able to remove redundant copies of certain genes that produce compounds associated with hangovers, and what’s more, add in copies of genes that code for resveratrol.  All of this assumes of course that you don’t mind genetically modified yeast in your wine, and that these compounds are the main culprit in wine hangovers. To the second point, there is a long tradition of wine consumption in moderation with food. This in turn leads to slower consumption, less intoxication, and less propensity for hangovers. The real issue is compounds called biogenic amines which are associated with headaches and allergic –type symptoms. (Histamine is a biogenic amine for example, which is why you take anti-histamines for allergies.) Biogenic amines typically develop in wine during malol...

Red wine headaches syndrome: Why is it still a problem?

If you are prone to headaches from red wine, would you drink wine made from genetically modified yeast if you knew you wouldn’t react to it? The problem of headaches from wine is one of the most frequent questions I get at lectures on wine and health. From an anti-aging point of view, evidence clearly points to red wine as a healthy habit. But if it gives you headaches, it just isn’t worth it. The good news is that we know what causes the headaches and how to make wine that doesn’t provoke them; the bad news is that almost no one is making wine that way.   The reasons behind this are enough to cause befuddle the brain and cause a headache all over again. You can thank University of British Columbia Biotechnology Professor Hennie van Vuuren for developing the solution. A sufferer of the red wine syndrome himself, Dr. van Vuuren has been working on the solution for some 15 years. The problem stems from compounds called biogenic amines, which include histamine and some rather...