Skip to main content

new research shows why red wine could reduce breast cancer risk

Last week's post referenced a population study that purported to show that any wine consumption even in moderation would increase the chances of getting beast cancer, but as I repeatedly point out the data is highly inconsistent. A new study further contradicts this by revealing some of the ways that resveratrol (from red wine) directly influences cancer-prone breast cells in human subjects. Researchers at the University of North Dalota recruited 39 women at increased risk for breast cancer (based on genetic analysis) and then monitored the effects of oral resveratrol supplementation for 12 weeks. Cells from the breast were sampled and analyzed, revealing that resveratrol helped activate what are called tumor suppressor genes.
This is particularly powerful information because studies of this type -prospective trials in human subjects with objectively verifiable results - provide the highest level of evidence. (In contrast, population studies such as the one referenced in last week's post are typically retrospective and based on self-reported consumption levels, which are known to be highly innaccurate.) There are certainly many things in red wine besides resveratrol, but this study reinforces the notion of healthy drinking and points to the benefits of wine.

Comments

Popular posts from this blog

Revisiting resveratrol: new findings rekindle anti-aging debate

Just when we thought the bloom was off the rosé for resveratrol, the anti-oxidant polyphenol from red wine with multiple anti-aging properties, along comes new research giving life to the debate. But first a bit of background: As I detailed in my book Age Gets Better with Wine , it is well-documented that wine drinkers live longer and have lower rates of many diseases of aging. Much or the credit for this has been given to resveratrol, though there isn’t nearly enough of it in wine to explain the effects. Nevertheless, I dubbed it the “miracle molecule” and when it was reported to activate a unique life-extension phenomenon via a genetic trigger called SIRT, an industry was born, led by Sirtris Pharmaceuticals, quickly acquired by pharma giant Glaxo. The hope was that resveratrol science could lead to compounds enabling people to live up to 150 years and with a good quality of life. But alas, researchers from other labs could not duplicate the results, and clinical studies disa...

Is wine a functional food?

Then again, didn’t all foods used to be functional? In the modern era of bulging waistlines, it would seem that nutrition has taken a back seat to processed foods engineered to tweak our taste buds and pleasure centers in the brain. And it is all too easy – and wrong – to cast wine as merely empty calories. But can we really consider wine to be a food, especially a nutritious one? To begin with, the term “functional food” means that it contains specific nutrients with identifiable health benefits. Sometimes these are added in, as with vitamins A and D in milk or calcium in orange juice. The way I see it, in a well-balanced diet there shouldn’t be a need for such enhancements. Wine for example naturally contains an abundance of antioxidant polyphenols, nutritionally vital ingredients that are increasingly lacking in many foods. A glass of wine with dinner on a daily basis is associated with longer life and better health by a variety of measures, a claim difficult to prove with vita...