Skip to main content

Wine and breast cancer: Here we go again

Yet another article about a possible link between wine and breast cancer is in the news, and as usual it is being widely quoted without any critical analysis or perspective. The article in question, a review of previously published studies, estimates that even a glass of wine per day increases risk of breast cancer and estimates that 1-2% of all breast cancer cases are attributable to light drinking alone. Rather than pick apart the article item by item, which would take all day since there are so many issues, I will highlight a few important things.

First, there are fundamental problems with the way that these types of studies are done, and reviewing them simply magnifies the underlying mistakes. Here’s the thing: in order to know if for example a glass of wine per day affected breast cancer risk, you would have to follow a large population of women who drink only wine, only a glass per day, every day, rarely more, rarely anything other than wine, and rarely not having a drink; this would need to be compared to a similar population who never drink, another who only drink beer, and so forth. But most people have mixed drinking patterns, they under-report their true level of drinking, and there is simply no reliable way to get any meaningful information. All we really know is that heavy drinking is bad.

Secondly, there are some populations of women in France who have traditionally consumed wine in moderate amounts and in a regular pattern. Their incidence breast cancer is dramatically lower than that of nondrinkers.

Third, breast cancer is nowhere near the leading cause of premature death in women; heart disease is far and away the biggest threat. It is well established that moderate wine consumption lowers heart disease risk, the net effect being overall reduction in risk of premature death.

Moderate wine consumption is also associated with lower odds of Alzheimer’s disease, osteoporosis, diabetes, and measurably improves quality of life and well-being. Wine drinkers outlive nondrinkers by about 5 years on average, and for most even if there is a fractional increase in breast cancer risk, the smart choice favors having a glass of wine with dinner and not stressing over it.

Comments

Popular posts from this blog

Versatile resveratrol: the ultimate skin care ingredient?

  Part 1 Recently I was honored to join Professors David Sinclair of Harvard and Joseph Vercauteren of the University of Montpelleir at an anti-aging symposium at the invitation of Mathilde Thomas of Caudalie in Paris. Caudalie has been using wine extracts (and specifically resveratrol) in their products for more than 15 years, after Vercauteren identified it in wine grape vines. Sinclair has become well known for his work identifying the role of sirtuin (SIRT) genes in anti-aging, and resveratrol as a natural sirtuin activator. While much remains to be proven, it is fair to say that science is finally beginning to have an impact on skin care. With an increasing understanding of what causes aging in skin cells and how botanical antioxidants such as resveratrol work at a molecular level, there is no excuse to use anti-aging skin care products that don’t multitask. Before delving into the potential benefits of resveratrol in skin care, it may help to review ho...

Revisiting resveratrol: new findings rekindle anti-aging debate

Just when we thought the bloom was off the rosé for resveratrol, the anti-oxidant polyphenol from red wine with multiple anti-aging properties, along comes new research giving life to the debate. But first a bit of background: As I detailed in my book Age Gets Better with Wine , it is well-documented that wine drinkers live longer and have lower rates of many diseases of aging. Much or the credit for this has been given to resveratrol, though there isn’t nearly enough of it in wine to explain the effects. Nevertheless, I dubbed it the “miracle molecule” and when it was reported to activate a unique life-extension phenomenon via a genetic trigger called SIRT, an industry was born, led by Sirtris Pharmaceuticals, quickly acquired by pharma giant Glaxo. The hope was that resveratrol science could lead to compounds enabling people to live up to 150 years and with a good quality of life. But alas, researchers from other labs could not duplicate the results, and clinical studies disa...