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Drink to your health: The wine-medical research connection

As I discovered in researching my book Age Gets Better with Wine, from ancient times it has been wed to health care and healthy living. In modern times, wine has come to support medical research more directly, through charity auctions and direct funding. Credit the granddaddy of them all, the Hospices de Beaune, for showing the way. But some wineries are taking it a step further. A few years ago I had the singular pleasure of attending the Staglin festival, which raises money for mental health research. What a glorious experience! All the top wineries in Napa participate, and although we had more wine that day than was strictly necessary for medical purposes, it was definitely a boon to my state of mind. Congrats to the Staglin family for raising awareness of an issue that many find uncomfortable and which suffers from a lack of research funding as a result. (The event is held every September, info on the Staglin website.) Ehlers Estate is another winery that ties its profits dire...

Wine and colon health: More than a gut feeling

The status of your intestinal tract may not be the sexiest of topics, but for those with problems such as inflammatory bowel disease it is of overriding importance. Whether or not you have a life-changing inflammatory disease, colon health deserves to be taken seriously - at least seriously enough to consider how wine and resveratrol fit in. It’s more good news, as you will have come to expect. Inflammatory bowel disease is a chronic, relapsing, tissue-destructive disorder for which there is no definitive cure. Patients typically undergo multiple surgeries and are on medication most of the time. It is also a difficult thing to study, but there is a model in mice in which the condition can be created by giving them a toxic compound called DSS. Various treatments can then be tested and markers of inflammation measured. A series of recent reports indicate that resveratrol and other wine polyphenols (again resveratrol shouldn’t get all the credit) can be quite helpful. Using resveratr...

Exercise your red wine habit for healthy aging

It seems there is no end to the list of benefits to red wine. One of the more interesting facets being explored is the question of how red wine compounds might work synergistically with other anti-aging behaviors to amplify the effect. We all know, for instance, that regular exercise is an important part of slowing down the aging process, but who would think of having a tipple before hitting the weight room? It’s not such a far-fetched idea according to some recent studies. Exercise, like most things that are good for us, must also be taken in moderation; too much and the overstressed muscles start releasing lactic acid and other deleterious compounds. With age the problem becomes worse, resulting in more oxidative stress which counteracts the benefits of working out in the first place! A study comparing oxidative stress in young vs old mice given resveratrol showed how this wine extract helps protect against these changes. Using several serum markers for oxidative stress, a group f...

The Prohibition Hangover: What a Headache!

One of the unanticipated joys of having a book in publication is meeting other like-minded authors. I had the opportunity to do just that at a book event held at the St. Helena Library in Napa Valley a couple of weeks ago, where the topic was wine books. It’s an annual event, designed to showcase the library’s extensive collection of wine literature. As it turns out, a theme for all three authors’ talks was prohibition. Attorney Richard Mendelson’s book, From Demon to Darling: A Legal History of Wine in America, describes the conflicted state of affairs that prohibition spawned. As I discuss in my book, temperance wasn’t always interpreted as abstinence, especially where wine was concerned. But banning all forms of alcohol outright turned out to be akin to trying to slay the Hydra of mythology, a multi-headed beast who grew two when one was cut off. The concept of healthy drinking, based on a tradition of wine with dinner, was lost. The history of wine and drinking is another one o...

Study Challenges Health Benefits of Alcohol: A Rebuttal

The news today is a study from France challenging the beneficial effects of alcohol, adding fuel to a debate we thought had flickered out some time ago. Dr. Boris Hansel of the Hopital de la Pitie in Paris, a specialist in cardiovascular disease prevention, acknowledged in an article in the European Journal of Clinical Nutrition that while moderate drinkers are in fact healthier, the alcohol doesn’t deserve the credit. The study was an analysis of lifestyle factors of nearly 150,000 adults, and largely confirmed the long-held theory that moderate drinkers (especially wine drinkers) are healthier. But Dr. Hansel’s conclusion was that the benefit was due to associated lifestyle factors, not the alcohol. Moderate drinkers do a lot of other healthy things too, such as exercise more and eat healthier diets, again most particularly wine drinkers. ( http://www.google.com/hostednews/afp/article/ALeqM5jx9U20jDoCjwpIdEN7PbNB32H3EA ) Is it really as simple as that? Not likely. For starters, th...

The Australian Heart Foundation blows the call on health benefits of wine

In a case of opinions in the rear-view mirror appearing larger than the mountain of evidence right in front of them, the Australian Heart Foundation recently released a position paper announcing that there are no health benefits to wine or dark chocolate. According to a spokesperson, the AHF is ''concerned about people thinking that in having red wine or dark chocolate that they are actually doing something to treat or prevent cardiovascular disease when the evidence doesn't support that.” The recommendation is based on a review of more than 100 studies over the past 10 years, and supposedly “puts to rest the popular belief that red wine, coffee and chocolate can keep cardiovascular problems at bay.” (http://www.themedguru.com/20100512/newsfeature/chocolate-coffee-red-wine-offer-no-health-benefits-86135104.html ) They couldn’t have gotten it more wrong. The thing is, there are more than 3,000 articles over the past 30 years or so on the subject, and I have looked at mo...

Time to reverse course with resveratrol?

It’s been an interesting week in the news for resveratrol. On the one hand, a new publication on how resveratrol affects the brain came out, adding to the very few clinical trials on the use of it as a supplement. On the other, Glaxo halted a clinical trial on resveratrol over safety concerns. Meanwhile, my piece in Web MD (http://www.webmd.com/skin-beauty/news/20100427/is-drinking-wine-a-key-to-antiaging?ecd=wnl_skin_0505100) garnered quite a lot of attention and brings us back to the question of whether we aren’t just better off drinking wine instead anyway. As I have mused about here before, clinical trial data on the use of resveratrol is all but absent, and what there is tends to show that it isn’t very well absorbed. So anyone bringing some clinical science to the field is to be congratulated. The study out this week actually measured blood flow to the brain during cognitive tasks, in other words things require thinking and concentration. Resveratrol improved blood flow and ra...