The promise of hangover-free wine has been in the news this week, based on new gene splicing techniques to manipulate the yeast used in fermentation. Using an enzyme called a “genome knife” researchers have been able to remove redundant copies of certain genes that produce compounds associated with hangovers, and what’s more, add in copies of genes that code for resveratrol. All of this assumes of course that you don’t mind genetically modified yeast in your wine, and that these compounds are the main culprit in wine hangovers. To the second point, there is a long tradition of wine consumption in moderation with food. This in turn leads to slower consumption, less intoxication, and less propensity for hangovers. The real issue is compounds called biogenic amines which are associated with headaches and allergic –type symptoms. (Histamine is a biogenic amine for example, which is why you take anti-histamines for allergies.) Biogenic amines typically develop in wine during malol...
Research in the area of wine and health has exploded in recent years and in this blog I sort through it to see what is really useful. For a definitive resource please refer to my book Age Gets Better with Wine: New Science for a Healthier, Better, and Longer Life.